Gibson, who has long petitioned to play Green Lantern on the big screen, would make his comic book movie debut in the Spider-Man universe movie.
The film, also starring Matt Smith and Jared Harris, began production this week in London.
The Daniel Espinosa-directed feature tells of the antihero Morbius the Living Vampire. Morbius is Dr. Michael Morbius, a scientist who suffered from a rare blood disease and attempted to cure himself to disastrous results. Instead of being cured, he became afflicted with a condition that was a form of vampirism, hitting him with the thirst for blood, along with fangs and super strength.
Leto will play Morbius, while Smith is set to portray the villain of the piece, Loxias Crown, Morbius’ best friend who also suffers from the blood disease. Arjona will play Morbius’ love interest, while Harris will portray Morbius’ mentor.
Gibson would play an FBI agent trying to hunt down the living vampire.